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目的探讨氨茶碱持续泵入联合胰岛素泵治疗慢性肺源性心脏病(CPHD)合并2型糖尿病(T2DM)的疗效。方法选择CPHD合并T2DM 104例,按数字随机法分为两组。治疗组(n=52):氨茶碱持续泵入+胰岛素泵。对照组(n=52):氨茶碱静脉滴注+诺和灵R持续静脉滴注。比较两组临床疗效及糖尿病控制情况:目标血糖时间、胰岛素用量、低血糖发生率、心功能。结果①治疗组总有效率为86.54%,对照组为67.31%,2组差异有统计学意义(P<0.05);②治疗组目标血糖达标快,低血糖发生率低,两组差异有统计学意义(P<0.05)。结论氨茶碱持续泵入联合胰岛素泵治疗CPHD合并T2DM,方法适宜,疗效显著,安全性高。
Objective To investigate the efficacy of aminophylline pumped into combined insulin pump in the treatment of chronic pulmonary heart disease (CPHD) with type 2 diabetes mellitus (T2DM). Methods 104 cases of CPHD complicated with T2DM were selected and divided into two groups according to the number randomization method. Treatment group (n = 52): aminophylline continued to pump + insulin pump. Control group (n = 52): Aminophylline intravenous infusion + Novo Ling R continuous intravenous infusion. The clinical efficacy and the control of diabetes were compared between the two groups: target blood glucose time, insulin dosage, incidence of hypoglycemia and cardiac function. Results ① The total effective rate was 86.54% in the treatment group and 67.31% in the control group, with significant difference between the two groups (P <0.05). ②The target blood glucose of the treatment group reached fast and the incidence of hypoglycemia was low. There was statistical difference between the two groups Significance (P <0.05). Conclusion Continuous infusion of aminophylline and insulin pump in the treatment of CPHD complicated with T2DM, the method is suitable, the curative effect is remarkable and the safety is high.