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目的探讨重症急性胰腺炎(SAP)患者QT间期的离散程度对判断心脏损害及预后判断的重要意义。方法回顾性分析我院收治的122例急性胰腺炎患者,其中SAP组46例,轻型急性胰腺炎(MAP)组76例,2组都统计出完整的心电图资料;另随机抽选38例健康体检者的心电图作为对照。分别测定122例患者和38例健康者的12导联心电图QT间期、QT间期离散度(QTd)、心率校正QTd(QTcd),并进行比较分析和推断。结果与其他2组相比较,SAP组在QTd、QTcd延长程度的差异非常明显,具有统计学意义(P<0.05);MAP组与对照组相比,QTd、QTcd无明显延长,差异不显著(P>0.05)。结论QTd、QTcd的变化可以作为评判SAP患者心功能状态及早期心脏损害的指标,对临床诊断、预后分析有重要意义。
Objective To investigate the significance of QT interval dispersion in judging cardiac damage and prognosis in patients with severe acute pancreatitis (SAP). Methods A retrospective analysis of 122 patients with acute pancreatitis admitted to our hospital, including SAP group 46 cases, 76 cases of light acute pancreatitis (MAP) group, two groups were statistics complete ECG data; the other a random sample of 38 cases of physical examination The ECG as a control. The 12-lead ECG QT interval, QTd interval and QTd (QTd) were measured in 122 patients and 38 healthy controls, respectively, and compared and analyzed. Results Compared with the other two groups, the difference of QTd and QTcd prolongation in SAP group was statistically significant (P <0.05). Compared with the control group, QTd and QTcd in MAP group were not significantly prolonged P> 0.05). Conclusion The changes of QTd and QTcd can be used as indexes to evaluate the cardiac function and early heart damage in patients with SAP, which is of great significance for clinical diagnosis and prognosis analysis.