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目的:观察甲钴胺联用前列地尔注射液治疗糖尿病周围神经病变的疗效。方法:选择糖尿病周围神经病变患者120例,常规血糖控制良好,按接诊先后随机分成治疗组及对照组,各60例。治疗组予甲钴胺联用前列地尔注射液治疗,对照组予甲钴胺治疗。治疗3个月后,观察两组治疗效果。结果:治疗3个月,治疗组显效48例,有效10例,无效2例,总有效率96%;对照组显效6例,有效18例,无效36例,总有效率40%,组间差异有统计学意义。结论:甲钴胺联用前列地尔注射液治疗糖尿病周围神经病变疗效好,用药安全。
Objective: To observe the efficacy of mecobalamin combined with alprostadil injection in the treatment of diabetic peripheral neuropathy. Methods: 120 patients with diabetic peripheral neuropathy were selected. The routine blood glucose control was good. The patients were randomly divided into treatment group and control group according to the admissions, each with 60 cases. The treatment group was treated with mecobalamin plus alprostadil and the control group with mecobalamin. After 3 months of treatment, the treatment effect was observed in both groups. Results: After treatment for 3 months, 48 cases were markedly effective in treatment group, 10 cases were effective and 2 cases were ineffective. The total effective rate was 96%. In the control group, 6 cases were markedly effective, 18 cases were effective, 36 cases were ineffective and the total effective rate was 40% There is statistical significance. Conclusion: Mecobalamin combined with alprostadil injection in the treatment of diabetic peripheral neuropathy has good efficacy and safety.