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目的:探讨乳果糖对亚临床肝性脑病的治疗作用.方法:具有慢性肝硬化病史,符合亚临床肝性脑病诊断条件的门诊或住院患者48例随机分为两组,每组24例,实验组给予乳果糖20ml,2次/d,另加复合维生素B、益肝灵常规口服;对照组给予复合维生素B2片、益肝灵2片,口服3次/d,1mo为1疗程,治疗前后分别进行数字连接实验、语言智商、操作智商检查,脑电图检查,血、尿、大便常规及肝功能检查.结果:实验组23例、对照组22例完成治疗并随访,实验组在数字连接实验、语言智商、操作智商方面有显著改善,而对照组无明显改善,实验组脑电图恢复正常12例,无效11例;对照组用药前后脑电图无显著变化.结论:乳果糖治疗亚临床肝性脑病有效.
Objective: To investigate the therapeutic effect of lactulose on subclinical hepatic encephalopathy.Methods: Forty-eight outpatients or inpatients who had a history of chronic liver cirrhosis and met the diagnostic criteria of subclinical hepatic encephalopathy were randomly divided into two groups (24 in each group) Group given lactulose 20ml, 2 times / d, plus compound vitamin B, Yigan conventional oral; control group given compound vitamin B2 tablets, Yiganling 2 tablets, oral 3 times / d, 1mo for a course of treatment before and after treatment The results of experimental group (n = 23) and control group (n = 22) completed the treatment and follow-up, and the experimental group was in digital connection Experimental, linguistic intelligence, the operation of IQ improved significantly, while the control group no significant improvement in the experimental group returned to normal in 12 cases of EEG, ineffective in 11 cases; control group before and after EEG had no significant changes.Conclusion: Clinical hepatic encephalopathy effective.