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对药物流产 (药流 )后再次妊娠的孕妇观察其妊娠期、分娩期并发症的发生情况及新生儿健康状况。并与有手术流产 (术流 )史的孕妇进行比较 ,探讨药流的安全性。方法 :同期内选择年龄 2 3～ 3 5岁的药流 (2 1 2例 )或术流 (2 0 1例 )后再次妊娠的健康妇女 ,进行前瞻性研究 ,观察其妊娠期并发症 (妊高征、自然流产、前置胎盘、胎盘早剥、过期妊娠 )与分娩期并发症 (产后出血、胎盘粘连、胎盘残留、胎膜不全、胎膜早破、胎儿窘迫等 )的发生情况以及新生儿的健康状况。结果 :妊娠期并发症 ,术流组 (2 0 .9% )明显高于药流组(1 2 .3 % ) ,差异有显著意义 (P<0 .0 5) ,其中先兆流产发生率术流组 (1 3 .4 % )明显高于药流组 (3 .8% ) ,差异有非常显著意义 (P=0 .0 0 0 ) ;分娩期并发症术流组 (1 7.4 % )与药流组(1 9.3 % )无显著性差异 ;妊娠结局术流组 (3 .5% )与药流组 (3 .8% )无显著性差异。认为药流对再次妊娠分娩与术流一样都是安全的 ,并且药流再次妊娠时妊娠期并发症明显低于术流。
Pregnant women who have been aborted after medical abortion (medical abortion) were observed the incidence of complications during pregnancy and childbirth, and the status of newborn’s health. And compared with pregnant women with surgical abortion (operation flow) history, to explore the safety of medical abortion. Methods: In the same period, healthy women aged 23 to 35 years old (221 cases) or reoperation (210 cases) were enrolled in this prospective study to observe the complications of pregnancy (pregnancy-induced hypertension Placental abruption, placental abortion, premature rupture of membranes, fetal distress, etc.), as well as the occurrence of neonatal complications such as postpartum hemorrhage, placental adhesion, placenta accreta, Health status. Results: The complications of pregnancy were significantly higher in operation group (20.9%) than in drug delivery group (12.3%) (P <0.05), and the incidence of threatened abortion Group (13.4%) was significantly higher than the drug flow group (3.8%), the difference was significant (P = 0.000); labor complications of childbirth group (7.4%) and drug flow group (9.3%) had no significant difference. There was no significant difference between pregnancy outcome group (3.5%) and drug delivery group (3.8%). The medical abortion is considered as safe for the second trimester of pregnancy and childbirth, and the complications of pregnancy during the third trimester of pregnancy are obviously lower than that of the operation.