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我院于1995年6月至1998年8月对丧失溶栓机会的老年急性心肌梗塞患者,应用低分子肝素治疗并做随访观察,现将结果报道如下。 对象与方法 1 病例选择 根据1979年世界卫生组织《缺血性心脏病的命名及诊断标准》选入50例70岁以上老年丧失溶栓机会的急性心肌梗塞的住院患者。剔除:①有出血倾象;②2个月内接受大手术或创伤;③活动性消化性溃疡;④严重的肝肾功能不全;⑤出血性脑卒中史,>6h至6个月的缺血性脑卒中(包括短暂脑缺血发作)。 2 方法 50例患者采用随机对照开放法分为2组,其中治疗组28例(男性21例,女性7例,平均年龄75.4±4.2岁);对照组22例(男性14例,女性8例,平均年龄74.8±4.6岁)。两组年龄、性别、梗塞面积和心功能改变均无显著差异
Our hospital from June 1995 to August 1998 for the elderly patients with thrombolytic failure of acute myocardial infarction, the application of low molecular weight heparin treatment and follow-up observation, the results reported below. Subjects and methods 1 case selection According to the 1979 WHO “name and diagnostic criteria for ischemic heart disease,” selected 50 cases of 70-year-old elderly patients with thrombolysis opportunities of acute myocardial infarction inpatients. Excluded: ① hemorrhage dumping; ② major surgery or trauma within 2 months; ③ active peptic ulcer; ④ severe liver and kidney dysfunction; ⑤ history of hemorrhagic stroke,> 6h to 6 months of ischemic Stroke (including transient ischemic attack). 2 Methods 50 patients were randomized controlled open group was divided into two groups, including 28 cases in the treatment group (21 males and 7 females, mean age 75.4 ± 4.2 years); control group of 22 patients (14 males and 8 females, Average age 74.8 ± 4.6 years). There were no significant differences in age, sex, infarct size, and cardiac function between the two groups