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目的:探讨基础卵泡刺激素值(bFSH)预测FSH正常的年轻不孕患者促排卵周期中卵巢反应性的价值。方法:回顾性分析2009年1～12月因男方因素或原因不明的年轻不孕症患者76例,且bFSH正常(≤8.5 mIU/ml),均采用重组人促卵泡激素针(r-FSH)促排卵治疗,共76个周期,分析bFSH与年龄、基础黄体生成素、雌二醇、促排卵用药的时间、用药总量以及卵泡个数、最大卵泡数,内膜厚度及妊娠结局之间的相关性。结果:bFSH与卵泡个数呈负相关(P<0.01),与内膜厚度呈正相关(P<0.05);促排卵治疗后14例临床妊娠,临床妊娠率为18.4%(14/76),妊娠组和非妊娠组bFSH值分别为(7.31±1.29)mIU/ml vs(6.98±0.51)mIU/ml,结果达统计学意义(P<0.01)。结论:较低的bFSH水平患者在年轻不孕症患者促排卵中能获得较多的卵泡数和较高的临床妊娠率,bFSH水平可能是预测bFSH正常且年轻的不孕患者卵巢反应性的一项较好指标。
Objective: To investigate the value of basal follicle stimulating hormone (bFSH) predicting the ovarian response during ovulation induction in young infertile women with normal FSH. Methods: A retrospective analysis of 76 infertile women with infertility due to unknown male factors (January to December 2009) and normal bFSH (≤8.5 mIU / ml) were performed using recombinant human follicle stimulating hormone (r-FSH) Ovulation induction, a total of 76 cycles, analysis of bFSH and age, basal LH, estradiol, ovulation induction time, the total amount of medication and the number of follicles, the largest number of follicles, intima thickness and pregnancy outcome between Correlation. Results: There was a negative correlation between bFSH and the number of follicles (P <0.01), and there was a positive correlation between bFGF and the thickness of the endometrium (P <0.05). After the ovulation therapy, the clinical pregnancy rate was 18.4% (14/76) The values of bFSH were (7.31 ± 1.29) mIU / ml vs (6.98 ± 0.51) mIU / ml respectively in the group of non-pregnant and non-pregnant women. The results were statistically significant (P <0.01). CONCLUSIONS: Patients with lower bFSH levels have more follicles and higher clinical pregnancy rates in ovulation induction in young infertility patients. The bFSH level may be one of the predictors of ovarian response in normal and young infertile women with bFSH Item is a good indicator.