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鼻孢子菌病人是由希伯氏鼻孢子菌感染引起的一种慢性肉芽肿性真菌病,世界各地均有零星报道。1979年本院李新章报道国内首例鼻孢子菌病的真菌学检查,现将该例的临床表现、治疗经过及经9年追踪的结果报道如下: 病例报告 患者陈××,男,27岁,广东高鹤县农民,1977年2月来诊。主诉反复鼻塞6～7年,流血性鼻涕,无臭。在当地作为“鼻息肉”曾行两次鼻息肉摘除术,术后均很快复发而来诊。经检查见双鼻腔填满红色肉芽样肿物,质脆,表面布满针尖大小的黄色小颗粒。用棉枝揩擦即可脱落,并有少许出血。基底位于左鼻腔侧壁及底壁,右鼻腔肿物基底位于鼻中隔。 经鼻分泌物涂片及活组织检查诊断为鼻孢子菌病,于1977年4月在2％Dicain表麻下经前鼻孔行肿物局部切除术。术后给予液氮冷冻治疗,半年后复发,
Rhinosporidiosis Rhinosporidiosis is a chronic granulomatous fungal disease caused by infection with Rhinosporidium Seeberi. It is reported sporadically all over the world. In 1979, Li Xinzhang of our hospital reported on the first case of mycosis in China. The clinical manifestations, treatment history, and results of the 9-year follow-up were reported as follows: Case Report Patient Chen X, male, 27 years old, Farmers in Gaohe County, Guangdong Province, visited the hospital in February 1977. Chief complaints repeated nasal congestion 6 to 7 years, bleeding nose, odorless. In the local area, as a “nasal polyp,” two nasal polyps have been performed and all patients have relapsed soon afterwards. Upon inspection, the double nasal cavity was filled with red granulation-like masses, which were brittle and covered with small yellow particles of the tip size. Wipe with cotton buds to fall off, and there is a little bleeding. The base is located on the side wall and the bottom wall of the left nasal cavity, and the base of the right nasal cavity is located in the nasal septum. Transnasal secretion smears and biopsy were diagnosed as rhinosporasis. In April 1977, local angioplasty was performed on the anterior nares under 2% Dicain. Give liquid nitrogen cryotherapy after surgery and relapse after six months.