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目的对不同病理类型肺癌患者行放射性核素骨显像,以观察骨转移的发生率及转移部位。方法1500例肺癌患者进行前后及后前位全身分段骨显像。骨显像剂为99Tcm,亚甲基二膦酸盐(MDP)。结果①1500例肺癌患者核素骨显像示骨转移者628例,其中中央型肺癌279例,周围型肺癌349例,总阳性率42%。②腺癌345例,鳞癌122例,小细胞癌75例,不同病理类型肺癌其骨转移发生率差异有非常显著意义(P<001)。③肺癌骨转移部位以肋骨为最多见(205例),其次为脊柱(133例),多发性128例,再者为骨盆、股骨、肩胛骨等。结论肺癌患者核素骨显像对肺癌的分期、不同病理类型治疗方案选择及预后评估均有重要的临床参考价值
Objective To perform radionuclide bone imaging in patients with different pathological types of lung cancer to observe the incidence of bone metastasis and the site of metastasis. Methods A total of 1500 patients with lung cancer underwent anterior and posterior anterior subluxural bone imaging. The bone imaging agent is 99 Tcm, methylene diphosphonate (MDP). Results Of the 11 500 lung cancer patients, 628 cases were found to have bone metastases. There were 279 central lung cancers and 349 peripheral lung cancers. The total positive rate was 42%. 2 There were 345 cases of adenocarcinoma, 122 cases of squamous cell carcinoma, and 75 cases of small cell carcinoma. The difference in the incidence of bone metastases between lung cancers with different pathological types was very significant (P<001). 3 The bone metastases of lung cancer were most common in ribs (205 cases), followed by spine (133 cases), multiple cases in 128 cases, and pelvis, femur, and scapula. Conclusion Radionuclide bone imaging for lung cancer patients has important clinical reference value for the staging of lung cancer, treatment options of different pathological types and prognosis evaluation.