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进行性肌营养不良症是一组有显著遗传因素、并以某些肌群非炎性进行性病变为主要特征的原发性肌肉疾病,严重者最终可致瘫痪。临床上根据病变肌群不同和临床特点不同将其分为若干类型,其共同临床表现为进行性肌无力。近来,国外一些学者使用电镜对某些类型的肌病作过研究,但临床分型混淆现象仍然存在。本文希望通过对病肌的电镜观察,了解不同类型肌营养不良症的超微结构病变特征,以期为临床确诊提供帮助,为深入研究本病病理提供参考。[材料和方法]病肌活检材料16例,其中假性肥大型9例、肢带型3例、面肩肱型3例、眼肌型1例。活检部位腓肠肌(10例)和三角肌(6例)。标本常规处理作电镜观察。[结果和讨论]各型肌病没有
Progressive muscular dystrophy is a group of primary muscular diseases characterized by significant genetic factors and predominantly non-inflammatory progressive lesions in certain muscle groups. In severe cases, paralysis can eventually result. Clinically based on the different lesions and clinical features of different groups will be divided into several types, the common clinical manifestations of progressive weakness. Recently, some foreign scholars using electron microscopy for some types of myopathy have been studied, but the clinical classification of confusion still exists. In this paper, we hope to observe the ultrastructural features of different types of muscular dystrophy through electron microscopic observation of the diseased muscle in order to provide help for the clinical diagnosis and provide a reference for further study of the pathology of this disease. [Materials and Methods] 16 cases of pathological muscle biopsy material, including 9 cases of pseudo-hypertrophy, limb-type 3 cases, 3 cases of face and shoulder-humeral, ocular muscle type in 1 case. Gastrocnemius biopsy site (10 cases) and deltoid muscle (6 cases). Specimens were treated by electron microscopy. [Results and discussion] There is no type of myopathy