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目的:探讨肾愈胶囊治疗痰瘀互结型肾病的作用机理。方法:复制大鼠原位性肾小球肾炎模型,观察肾愈胶囊对原位性肾小球肾炎大鼠模型尿蛋白、血脂、血浆蛋白、血肌酐、尿素氮的影响。结果:肾愈胶囊具有明显降低原位性肾小球肾炎模型大鼠尿蛋白、血脂作用,并能改善低蛋白血症。结论:上述作用是肾愈胶囊治疗痰瘀互结型肾病的主要机制。
Objective: To explore the mechanism of Shenyu capsule in the treatment of spastic sympathetic nephropathy. METHODS: Rat models of in situ glomerulonephritis were replicated and the effects of Shenyu capsules on urinary protein, blood lipids, plasma protein, serum creatinine, and urea nitrogen in rats with orthotopic glomerulonephritis were observed. Results: Shenyu Capsule can significantly reduce the urinary protein and blood lipids in the rat model of in situ glomerulonephritis and improve hypoproteinemia. Conclusion: The above-mentioned effect is the main mechanism of Shenyu capsule in treating phlegm-conjunctival nephropathy.