目的研究栀子Gardenia jasminoides的干燥成熟果实中单萜类化学成分。方法采用多种柱色谱方法分离纯化,通过理化常数测定和光谱分析鉴定化合物的结构。结果从栀子果实80%乙醇提取物中分离得到了12个单萜类化合物,分别鉴定为jasminoside B(1)、jasminoside G(2)、jasminodiol(3)、(7R)-6-羟甲基-1,1,5-三甲基环己-3-烯酮(4)、(7S)-6-羟甲基-1,1,5-三甲基环己-3-烯酮(5)、bornyl-6-O-β-D-xylopyranosyl-β-D-glucopyranoside(6)、(10R,11R)-栀子二醇(7)、(10S,11S)-栀子二醇(8)、(5S,9S)-gardenate A(9)、(5R,9R)-gardenate A(10)、jasminoside E(11)、5,6-二羟甲基-1,1-二甲基环己-4-烯酮(12)。结论化合物5、6、8、10和12为首次从栀子中分离得到。 Aim To study the monoterpene chemical constituents of dried ripe fruit of Gardenia jasminoides. Methods The compounds were separated and purified by a variety of column chromatography methods. The structures of compounds were identified by physico-chemical constants and spectral analysis. Results Twelve monoterpenoids were isolated from 80% ethanol extract of gardenia fruit and identified as jasminoside B (1), jasminoside G (2), jasminodiol (3), (7R) -6-hydroxymethyl (4), (7S) -6-hydroxymethyl-1,1,5-trimethylcyclohex-3-enone (5) , Bornyl-6-O-β-D-xylopyranosyl-β-D-glucopyranoside (6), (10R, 11R) (5S, 9S) -gardenate A (9), (5R, 9R) -gardenate A (10), jasminoside E (11), 5,6-dimethylol- - enone (12). Conclusion Compounds 5, 6, 8, 10 and 12 were isolated from gardenia for the first time.