论文部分内容阅读
目的了解近年来高中生乙肝病毒感染状况,为该人群的今后预防对策提供依据。方法选择某高中部2006-2009年入学新生2 756名,用酶联免疫吸附(ELISA)法检测乙肝HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc。结果 2 756份血清标本中HBsAg阳性率为4.46%;2006-2009年阳性率为5.67%~2.73%;男女性别间阳性率为3.08%、2.3%。检测出HBsAg阳性123份血清标本中5种感染模式,以HBsAg、抗-HBe、抗-HBc三项阳性最高为47.15%,其次HBsAg、抗-HBc二项阳性为28.46%,HBsAg、HBeAg、抗-HBc三项阳性为16.26%,HBsAg、HBeAg二项阳性4.88%和HBsAg阳性为3.25%。结论近年来高中新生HBsAg感染率呈逐年下降趋势;HBsAg阳性者中HBeAg阳性率为21.14%,是可能导致乙肝病毒传播的危险因素,加强对HBV携带者的管理和采取乙肝疫苗预防接种等措施,对高中新生乙型肝炎防治具有重要意义。
Objective To understand the status of hepatitis B virus infection in high school students in recent years and provide the basis for future prevention measures of this population. Methods A total of 2 756 freshmen were enrolled in a high school from 2006-2009. HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc were detected by enzyme linked immunosorbent assay (ELISA). Results The positive rate of HBsAg in 2 756 serum samples was 4.46%. The positive rate in 2006-2009 was 5.67% -2.73%. The positive rate of male and female was 3.08% and 2.3% respectively. HBsAg, anti-HBe and anti-HBc were 47.15%, followed by HBsAg and anti-HBc positive 28.46%, HBsAg, HBeAg, anti-HBeAg -HBc three positive 16.26%, HBsAg, HBeAg 4.88% positive and HBsAg positive 3.25%. Conclusions The HBsAg infection rate of high school freshmen has been declining year by year in recent years. The positive rate of HBeAg in HBsAg positive patients is 21.14%, which may lead to the risk of hepatitis B virus transmission, strengthen the management of HBV carriers and vaccination with hepatitis B vaccine, It is of great significance to the prevention and treatment of hepatitis B in high school freshmen.