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目的:评价中西医结合治疗小儿支原体肺炎(mycoplasma pneumonia,MPP)的临床疗效。方法:纳入80例MPP患儿,按随机数字表分成治疗组和对照组,每组各40例。对照组采用西医常规治疗,治疗组采用西医常规治疗结合清肺通络中药口服,同时辅以穴位敷贴治疗,治疗周期为10 d。评价两组患儿的疾病疗效及中医证候疗效,比较两组患儿的主要症状及肺部体征评分。结果:治疗后,两组的总有效率均为100%,而对照组的疾病疗效愈显率为77.50%、治疗组为97.50%,两组疗效比较差异有统计学意义(P<0.01);对照组的中医证候疗效愈显率为62.50%,治疗组为90.00%,两组疗效比较差异有统计学意义(P<0.01)。治疗后,两组患儿的发热、咳嗽、痰壅、气喘及肺部体征评分较治疗前均明显降低(P<0.01),且治疗组患儿咳嗽、痰壅评分低于对照组(P<0.01);两组患儿的主症总积分均显著降低(P<0.01),且治疗组患儿的积分低于对照组(P<0.01)。结论:运用中医清肺通络法结合西医常规疗法治疗MPP具有较好的临床疗效,能够有效改善患儿的临床症状。
Objective: To evaluate the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of mycoplasma pneumonia (MPP) in children. Methods: 80 children with MPP were enrolled. According to the random number table, they were divided into treatment group and control group, 40 cases in each group. The control group was treated with conventional western medicine. The treatment group was treated with routine western medicine combined with Qingfei Tongluo Chinese medicine, supplemented with acupuncture point application, and the treatment period was 10 days. Efficacy of the two groups of children with disease evaluation and efficacy of TCM syndromes were compared, and the main symptoms and signs of lung in both groups were compared. Results: After treatment, the total effective rate was 100% in both groups, while the cure rate of the control group was 77.50%, and the treatment group was 97.50%. The difference between the two groups was statistically significant (P <0.01). The effective rate of TCM syndromes in the control group was 62.50%, and the treatment group was 90.00%. There was significant difference between the two groups (P <0.01). After treatment, the fever, cough, phlegm, asthma and lung signs in both groups were significantly lower than those before treatment (P <0.01), and the cough and phlegm score in the treatment group were lower than those in the control group (P < 0.01). The main symptom score of both groups was significantly lower (P <0.01), and the scores of the treatment group were lower than those of the control group (P <0.01). Conclusion: The use of traditional Chinese medicine Qingfei Tongluo method in combination with conventional Western medicine treatment of MPP has good clinical efficacy, can effectively improve the clinical symptoms of children.