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为探讨缺血再灌流损伤脊髓传导功能的变化及２ 氨基膦酸基戊酸（ＡＰＶ）的影响，１２ 只家兔随机均分为缺血６０ｍ ｉｎ 组和缺血６０ｍ ｉｎ＋ ＡＰＶ 治疗组，以选择性腰动脉阻断法模拟脊髓缺血再灌流损伤，观测各组在缺血前、缺血时及再灌流时皮层体感诱发电位（ＣＳＥＰ）和运动诱发电位（ＭＥＰ）的变化。结果：缺血（１３．２±４．０）ｍ ｉｎ、（２０．６±５．７）ｍ ｉｎ 时ＣＳＥＰ、ＭＥＰ分别消失，再灌流８ｈ 后ＡＰＶ 治疗组ＣＳＥＰ和ＭＥＰ的Ｎ１ 和Ｐ１ 波峰潜时较损伤组明显缩短。表明ＣＳＥＰ能更早地反映脊髓损伤情况，ＭＥＰ则对脊髓损伤的预后功能判断更有意义，ＡＰＶ能改善损伤脊髓的感觉运动传导功能
To investigate the changes of spinal conduction function and the effect of 2-aminophosphonic acid (APV) on ischemia-reperfusion injury, 12 rabbits were randomly divided into ischemia 60m in group and ischemia 60m in + APV group The lumbar spinal cord ischemia-reperfusion injury was simulated by lumbar artery occlusion. The changes of cortex somatosensory evoked potential (CSEP) and motor evoked potential (MEP) were observed before ischemia, ischemia and reperfusion. Results: The CSEP and MEP disappeared at ischemia (13.2 ± 4.0) m in and (20.6 ± 5.7) m in, respectively. The peak of N1 and P1 of CSEP and MEP in APV treatment group after 8 h of reperfusion Compared with the injury group was significantly shorter. It shows that CSEP can reflect the condition of spinal cord injury earlier and MEP is more meaningful to determine the prognosis of spinal cord injury. APV can improve the sensory motor conduction function of injured spinal cord