以血糖值为评价指标,以小鼠为动物模型,对癞葡萄皂甙的降血糖作用进行了探讨。实验结果表明,粗皂甙对正常小鼠没有显著不良影响,对糖尿病小鼠的降血糖作用非常显著。通过不同剂量癞葡萄皂甙对小鼠降糖效果的影响可知:低、中剂量组具有更好的降糖效果。通过糖耐量实验可知,癞葡萄皂甙对试验性糖尿病小鼠的糖耐量具有显著的增强作用。 Taking blood glucose as the evaluation index and using mice as an animal model, the hypoglycemic effect of saponin of Lycium barbarum was investigated. The experimental results showed that crude saponin had no significant adverse effects on normal mice, and the hypoglycemic effect on diabetic mice was very significant. The effect of different doses of saponin from saponin on the hypoglycemic effect of mice is known: the low and middle dose groups have better hypoglycemic effect. Through the glucose tolerance test, it can be seen that the ginsenosides of the grape have a significant enhancement effect on the glucose tolerance of experimental diabetic mice.