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糖尿病患者应用胰岛素治疗,即要防止由于胰岛素不足引起的代谢异常,又要不引起低血糖。如何掌握最适量的胰岛素是非常重要的。但以往所应用的胰岛素多次注射疗法及胰岛素持续注射疗法都很难精确地控制血糖。现已证实,血中胰岛素、胰高血糖素及葡萄糖的浓度具有短周期性变化(约10～13分),这与β细胞分泌胰岛素的周期性有关。Matthews等将这种胰岛素周期性分泌的现象应用于糖尿病的治疗,并进行胰岛素间歇注射法与持续
Diabetes patients with insulin therapy, that is, to prevent metabolic disorders due to lack of insulin, but also does not cause hypoglycemia. How to master the optimal amount of insulin is very important. However, in the past, multiple insulin injections and continuous insulin injections were difficult to control accurately. Has confirmed that the blood insulin, glucagon and glucose concentration with short-term changes (about 10 to 13 points), which is related to the beta cells secrete insulin cycle. Matthews and other cyclical secretion of this insulin will be applied to the treatment of diabetes, and intermittent insulin injection and sustained