采用光、电镜,对高原(格尔木地区,海拔2 800米)世居的6位男性藏族青年的皮肤进行组织学观察,结果提示:1、表皮角质层明显增厚,为0.79mm,其余各层细胞总厚度为0.9mm,两者之比为1:1.14;表皮各层细胞内和细胞间有较多的黑色素颗粒;郎格罕细胞较少见,胞质突起少而短。2、基底小脚粗、长,呈分枝状伸向真皮深层,其内有较多的小泡。3、真皮层内胶原纤维致密,基质减少;小血管内皮细胞增生,胞质绒毛呈多形态,基膜较宽。 Using light and electron microscopy, the histological observation of the skin of 6 male Tibetan youth living in the plateau (Golmud region, 2 800 m above sea level) showed that: 1. The stratum corneum of the epidermis was thickened to 0.79 mm, and the remaining layers The total cell thickness of 0.9mm, the ratio between the two is 1: 1.14; intraepithelial layers of cells and cells have more melanin particles; Langerhans cells less common, cytoplasmic processes less and shorter. 2, basal feet thick, long, was branched into the deep dermis, which has more vesicles. 3, dermal collagen fibers dense, matrix reduction; small vascular endothelial cell hyperplasia, cytoplasmic villi was multi-morphology, the basement membrane wider.