克隆病,现在认为不仅见于末端回肠,而且好发于小肠、结肠,进而在消化道其它部位也能发生病变的疾病。可是,有关克隆病的胃与十二指肠病变的病例报告甚少,特别在日本几乎未见报道。最近,作者对3例克隆病患者的上消化道进行了详细检查,发现上消化道均有多发性微小糜烂或浅溃疡,活检证明2例系微小非干酪性肉芽肿;另1例伴有多核巨细胞的肉芽肿样病变。 Crohn’s disease, now considered not only seen in the distal ileum, but also occur in the small intestine, colon, and then in other parts of the digestive tract lesions can also occur disease. However, little is known about the cases of gastric and duodenal lesions associated with Crohn’s disease, especially in Japan. Recently, the author of the three patients with Crohn’s disease in the upper gastrointestinal tract were examined in detail and found that the upper digestive tract were multiple micro-erosion or superficial ulcer, biopsy showed that 2 cases of non-small granulomatous cases; the other with multi-core Giant granuloma-like lesions.