胰岛素是胰脏分泌的一种蛋白质激素,在生物体内对物质代谢起调节作用,在临床上作为治疗糖尿病的特效药被广泛应用。药用胰岛素主要来源于动物,在临床应用中,它存在着异体蛋白的抗原性、作用时间短和稳定性差等弱点。各国学者在研究胰岛素的结构与功能的基础上,对胰岛素分子进行修饰和改造,以改变其某些性质,提高其应用价值。本实验曾用右旋糖酐共价修饰胰岛素,修饰胰岛素,降血糖能力提高,延长 Insulin is a protein hormone secreted by the pancreas. It plays a regulatory role in the metabolism of substances in the body and is widely used as a cure for diabetes in the clinic. Medicinal insulin is mainly derived from animals, in clinical applications, it has the antigenicity of allogeneic protein, the role of short time and poor stability and other weaknesses. On the basis of studying the structure and function of insulin, scholars all over the world have modified and modified insulin molecules to change some of their properties and improve their application value. This experiment has used dextran covalent modification of insulin, modified insulin, hypoglycemic ability to improve and extend