四、酮体供能与酸中毒 (一)何谓酮体: 酮体是脂肪酸代谢的正常中间产物,在肝脏生成,在肝外组织(如心、肾、脑等)氧化,是这些组织供能的物质之一。酮体包括:乙酰乙酸、β-羟丁酸、丙酮。三者之间的关系是:乙酰乙酸加氢还原变成β-羟丁酸,脱氢氧化又变成乙酰乙酸;乙酰乙酸脱羧(-CO_2)变成丙酮,但丙酮不能再变回乙酰乙酸。如下 Fourth, ketone body energy supply and acidosis (a) what is the ketone body: ketone body is the normal intermediate of fatty acid metabolism, generated in the liver, in extrahepatic tissues (such as heart, kidney, brain, etc.) oxidation is the organization for energy One of the substances. Ketones include acetoacetate, beta-hydroxybutyrate and acetone. The relationship between the three is: acetoacetate hydroperoxide into β-hydroxybutyric acid, dehydrogenation and turn into acetoacetate; acetoacetate decarboxylation (-CO_2) into acetone, but acetone can not change back to acetoacetate. as follows