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心脏的电活动是由动作电位的产生形成的,而动作电位的形成是由各离子流内流和外流产生的,当心肌缺血时,由于心肌细胞内外环境的变化,使得各离子流,分子特性发生变化,而且这种变化在心肌不同部位是不一致的,使得各部位的动作电位形态、振幅、时程的变化程度都不一样,形成了电的异质性,故产生自律性增高或折返,发生室性心律失常。由于各离子流是互相作用,互相影响的,目前研究由于“方法”所限,揭示的是以某个离子流为特征变化引起的室性心律失常,其具体的启动机制仍不清楚,要弄清楚各离子流是怎样整体协调、整体变化而发生室性心律失常的,应从“整体”上加以研究。
The electrical activity of the heart is formed by the action potential, and the action potential is formed by the influx and outflow of the ion currents. When the myocardium is ischemia, due to the changes of the internal and external environment of the myocardial cells, the ion currents, molecules Characteristics change, and this change in different parts of the myocardium is inconsistent, making the various parts of the action potential morphology, amplitude, duration changes are not the same, the formation of the heterogeneity of electricity, it has increased self-discipline or reentry , Occurrence of ventricular arrhythmia. As the ion currents interact with each other and influence each other, the current study is limited by the “method”, which reveals a ventricular arrhythmia caused by the change of an ion current. The specific activation mechanism is still unclear. To figure out how the overall flow of ion flow coordination, the overall change in the occurrence of ventricular arrhythmias, should be from the “whole” to be studied.