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目的：探讨急性髓细胞白血病（ＡＭＬ）表达淋巴系标志的意义。方法：用碱性磷酸酶抗碱性磷酸酶桥联酶标技术（ＡＰＡＡＰ法）检测３８例ＡＭＬ的２４种抗原的表达情况，其中２１例同时作核型分析。结果：３０例患者仅表达髓系标志（Ｌｙ－ＡＭＬ），８例患者同时表达髓系及淋巴系标志（Ｌｙ＋ＡＭＬ）。Ｌｙ＋ＡＭＬ作核型分析６例，其中５例核型异常。治疗４例，仅１例完全缓解。结论：Ｌｙ＋ＡＭＬ异常核型发生率高，患者预后差。
Objective: To explore the significance of lymphoid markers expressed in acute myeloid leukemia (AML). Methods: The expression of 24 antigens in 38 cases of AML was detected by alkaline phosphatase anti-alkaline phosphatase bridging (APAAP) method. Among them, 21 cases were simultaneously analyzed by karyotype. RESULTS: Thirty patients only expressed myeloid markers (Ly-AML). Eight patients also expressed myeloid and lymphoid markers (Ly+AML). Ly+AML was used for karyotype analysis in 6 cases, including 5 cases of karyotype abnormalities. Four patients were treated and only one patient achieved complete remission. Conclusion: Ly+AML has a high incidence of abnormal karyotypes and poor prognosis.