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一、基因疫苗基因疫苗指的是DNA疫苗,即将编码外源性抗原的基因插入到质粒上,然后将质粒直接导入人或动物体内,让其在宿主细胞中表达抗原蛋白,诱导机体产生免疫应答。抗原基因在一定时限内的持续表达,不断刺激机体免疫系统,使之达到防病的目的。基因疫苗包括以下几种类型:①多肽或亚单位疫苗;②颗粒载体疫苗;③病毒活载体疫苗;④细菌活载体疫苗;⑤基因重配疫苗;⑥基因缺失疫苗,如乙肝疫苗。
First, the gene vaccine Gene vaccine refers to the DNA vaccine, the gene encoding exogenous antigens will be inserted into the plasmid, and then the plasmid directly into human or animal body, so that the expression of antigen in the host cell protein to induce the body to produce immune response . Antigen gene in a certain period of continuous expression, continue to stimulate the body’s immune system, so as to achieve the purpose of disease prevention. Gene vaccines include the following types: (1) polypeptides or subunit vaccines; (2) particle carrier vaccines; (3) virus live carrier vaccines; (4) bacterial live carrier vaccines; (5) gene reassortant vaccines; (6) gene-deleted vaccines such as hepatitis B vaccines.