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目的研究血清hCG、血浆ET与妊高征的关系。方法采用放免法测定45例妊高征孕妇和48例正常孕晚期妇女血清hCG和血浆ET的值。结果妊高征孕妇血清hCG、ET值明显升高,与正常孕晚期妇女相比差异显著(P<001)。随病情加重其数值进行性升高。血清hCG值和血浆ET值呈正相关(r=0813)。结论hCG升高、ET升高可作为诊断妊高征以及判断病情轻重的指标。说明胎盘缺血、缺氧、滋养叶细胞增生,血管内皮损害仍然是妊高征发生发展的重要环节
Objective To study the relationship between serum hCG, plasma ET and pregnancy induced hypertension. Methods The serum levels of hCG and ET in 45 pregnant women with PIH and 48 normal pregnant women were measured by radioimmunoassay. Results The serum levels of hCG and ET in pregnant women with PIH were significantly higher than those in normal pregnant women (P <001). As the disease aggravates its value increases. There was a positive correlation between serum hCG level and plasma ET level (r = 0. 813). Conclusions High hCG and elevated ET may be used as indicators for the diagnosis of PIH and the severity of the disease. Description of placental ischemia, hypoxia, trophoblast cell proliferation, vascular endothelial damage is still an important part of the development and progression of pregnancy-induced hypertension