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目的观察卡前列素氨丁三醇注射液防治瘢痕子宫合并前置胎盘再次剖宫产术中出血的效果。方法选取2015年3月-2016年3月该院收治的瘢痕子宫合并前置胎盘再次剖宫产患者104例作为研究对象,按照随机、均等的原则分为观察组和对照组,每组各52例。对照组采用缩宫素和宫腔填纱,观察组在对照组基础上联合卡前列素氨丁三醇注射液。观察两组患者不同时间出血量、临床指标,统计产后出血、纱条填塞和术后输血例数,血红蛋白(HB)水平和红细胞(RBC)计数。结果观察组患者术中、术后2 h、术后24 h出血量显著低于对照组(P<0.05);观察组患者手术、住院、术中止血时间显著低于对照组(P<0.05),术后24 h尿量显著高于对照组(P<0.05);观察组患者产后出血、纱条填塞和术后输血例数显著低于对照组(P<0.05),产后24 h两组HB水平和RBC计数显著低于产前(P<0.05),且观察组显著高于对照组(P<0.05)。结论卡前列素氨丁三醇注射液可有效减少瘢痕子宫合并前置胎盘再次剖宫产患者术中及术后出血量,减少术后出血发生率。
Objective To observe the effect of carboprost trometamol injection in preventing cesarean section with placenta previa and cesarean section bleeding again. Methods From March 2015 to March 2016, 104 cases of cesarean section patients with scar uterus and placenta accreta treated in our hospital were selected as the study subjects, and divided into observation group and control group according to the principle of randomization and equality. example. The control group was treated with oxytocin and uterine filling, and the observation group was treated with carboprost tromethamine injection on the basis of the control group. The bleeding volume, clinical indicators, postpartum hemorrhage, gauze tamponade and postoperative blood transfusion, hemoglobin (HB) level and erythrocyte count (RBC) were observed in two groups. Results The bleeding volume of the observation group was significantly lower than that of the control group (P <0.05) at 2 h after operation and 24 h after operation. The operation, hospitalization and intraoperative bleeding time in the observation group were significantly lower than those in the control group (P <0.05) (P <0.05). The incidence of postpartum hemorrhage, gauze packing and postoperative blood transfusion in the observation group were significantly lower than those in the control group (P <0.05) (P <0.05), and the observation group was significantly higher than the control group (P <0.05). Conclusion Carbiodide trometamol injection can effectively reduce intraoperative and postoperative bleeding in cesarean section patients with scar uterus plus placenta previa, and reduce the incidence of postoperative bleeding.