近十年来已报道冠状血管运动张力改变和血管内血栓在发生心肌缺血中的作用。晚近认为,这些动力因素与动脉粥样硬化病变两者相结合为大多数患者冠状血流急性减少的原因。少数患者的冠状血管痉挛伴或不伴血栓形成亦已被证实为心肌缺血的致病因素。人类与动物研究资料显示,冠状动脉内血栓主要由血小板组成,本文旨在综述血小板功能以及血小板和血管壁间异常作用与缺血性心脏病的关系。 Over the past decade has reported changes in coronary vascular motor tension and intravascular thrombosis in the role of myocardial ischemia occurred. Recently considered that the combination of these motility factors and atherosclerotic lesions is responsible for the acute reduction in coronary blood flow in most patients. A small number of patients with coronary vasospasm or without thrombosis has also been identified as a causal factor in myocardial ischemia. Human and animal research data show that coronary thrombosis is mainly composed of platelets, this article aims to review the function of platelets and platelet and vessel wall abnormalities and ischemic heart disease.