肥大细胞在动脉粥样硬化中发挥着多重作用 ,特别是在不稳定斑块中起着关键作用。肥大细胞通过多种机制被激活后释放各种介质 ,促进泡沫细胞形成 ,影响动脉粥样斑块内细胞外基质的合成与降解 ,促使斑块内新生血管形成 ,这些过程都与动脉粥样硬化的发生发展密切相关 Mast cells play a multiple role in atherosclerosis, especially in unstable plaques. Mast cells are activated through a variety of mechanisms to release a variety of media, and promote the formation of foam cells, affecting the synthesis and degradation of extracellular matrix within atherosclerotic plaque, prompting neovascularization within the plaque, these processes are associated with atherosclerosis The occurrence and development are closely related