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例1:女,2岁。因发热3个月入院。患儿病后半个月,躯干部出现暗红色皮疹。消退后局部留有白斑,继之出现肝、脾、淋巴结肿大。查体:T36.6℃,躯干部皮肤散在暗红色斑丘疹,压之褪色,中央有小凹,可见皮疹脱落后遗留的白斑。肝右肋下3cm,脾左肋下2cm。X线片:颅骨可见散在数个大小不等凿孔状透亮区,边缘清楚,无硬化改变;髂骨、肱骨和股骨近端可见多发的大小不等、不规则破坏区;双肺散在小斑点或粒状影。皮疹压片病理检查:符合组织细胞增生症X,核型46XX,染色体无异常。血IgM1.81mg/L,C_31820mg/L。骨髓检查正常。“OT”1:2000(一)。给予强的松加长春新碱治疗一周后精神、饮食好转,全身皮疹消失;一个月后肝肋下1.5cm,脾未扪
Example 1: Female, 2 years old. 3 months due to fever admitted to hospital. Half a month after the illness in children, the body appeared dark red rash. After the disappearance of local left white spot, followed by liver, spleen, lymph nodes. Physical examination: T36.6 ℃, trunk skin scattered in dark red rash, pressure fade, the central concave, visible left after the skin rash off white. Liver right rib 3cm, spleen left rib 2cm. X-ray: the skull scattered in a number of sizes ranging from the bored translucent area, the edge clear, no hardening change; ilium, humerus and proximal femur can be seen in multiple sizes, irregular damage area; scattered lungs in small spots Or granular shadow. Rash tablet pathological examination: in line with histiocytosis X, karyotype 46XX, no abnormal chromosomes. Blood IgM1.81mg / L, C_31820mg / L. Bone marrow examination is normal. “OT” 1: 2000 (a). Given prednisone plus vincristine treatment after a week of spirit, diet improved, the whole body rash disappeared; a month after the rib ribs 1.5cm, the spleen is not palpable