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目的分析酮症倾向的2型糖尿病患者的临床特点。方法 80例有酮症倾向的2型糖尿病患者为A组,95例无酮症倾向的2型糖尿病患者为B组,75例1型糖尿病患者为C组,对三组患者的临床症状及其相关生化指标和影响因素进行统计学分析。结果 A组患者的发病率与空腹血胰岛素、餐后2 h血胰岛素、胰岛素抵抗指数(HOMA-IR)、冠状动脉病变、总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白胆固醇(LDL-C)的含量呈正相关(P<0.05),而与血清中高密度脂蛋白胆固醇(HDL-C)的含量呈负相关(P<0.05),而B组以及C组的发病率与空腹血胰岛素、餐后2 h血胰岛素、HOMA-IR、冠状动脉病变、TC、TG和LDL-C的含量之间无相关性(P>0.05)。结论以酮症起病的初发2型糖尿病患者的空腹血糖水平、餐后血糖以及HOMA-IR都处于较高的水平,同时患者通常伴有高脂血症。
Objective To analyze the clinical features of patients with type 2 diabetes who are predisposed to ketosis. Methods Eighty patients with ketosis-prone type 2 diabetes were Group A, 95 patients with type 2 diabetes without ketosis tended to Group B, and 75 patients with Type 1 diabetes were Group C. The clinical symptoms of the three groups of patients and their Related biochemical indicators and influencing factors for statistical analysis. Results The incidence of patients in group A was positively correlated with fasting blood insulin, postprandial insulin 2 h, insulin resistance index (HOMA-IR), coronary artery disease, total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (P <0.05), but negatively correlated with the content of high density lipoprotein cholesterol (HDL-C) in serum (P <0.05), while the incidences of group B and group C were significantly higher than those of fasting There was no correlation between insulin, postprandial blood insulin, HOMA-IR, coronary artery disease, TC, TG and LDL-C levels at 2 h postprandial (P> 0.05). Conclusion The fasting blood glucose, postprandial blood glucose, and HOMA-IR in patients with newly diagnosed type 2 diabetes mellitus are at a high level, and patients are often associated with hyperlipidemia.