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目的:对肝动脉栓塞后,门静脉分支对肝癌的营养情况进行观察。方法:将BrdU注入24例肝癌病人将被切除肝 段的门静脉分支内,标本用BrdU单克隆抗体进行免疫组化染色,然后用标记指数(L1)分析,同时检测被标记的S-期细胞分布。结果:TAE(动脉导管栓塞)室病人的L1值比没有TAE的病人高五倍,有显著差别(P<0.001=,标记的细胞不仅分布在肿瘤的周边部分还分布在中心部分。结论:在TAE后的阶段,门静脉对残存的肝癌的血供发挥主要的作用.肝癌切除后的化疗不仅通过肝动脉而且应通过门静脉.
Objective: To observe the nutritional status of liver cancer after the hepatic artery embolization and portal vein branch. Methods: BrdU was injected into the portal vein of 24 patients with liver cancer. The specimens were stained with BrdU monoclonal antibody for immunohistochemistry, and then analyzed by labeling index (L1). Meanwhile, the distribution of labeled S-phase cells . Results: In patients with TAE, the value of L1 was five times higher than that of patients without TAE (P <0.001), and the marked cells distributed not only in the peripheral part but also in the central part of the tumor.Conclusion: After the TAE stage, the portal vein plays a major role in the blood supply to the residual liver cancer, which is not only through the hepatic artery but also through the portal vein after resection of the liver cancer.