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经颅多普勒(TCD)是一种非侵入性测定脑动脉血流速率的超声技术。血管管径大小、顺应性和压力梯度等血液动力学因素是决定血流速率的主要因素,其他相关因素有年龄、动脉CO_2分压、血细胞比容(Ht)及纤维蛋白原含量。但以往对年龄、氧含量和血液流变学因索的相对重要未作过检测。作者在患慢性肾衰的病人(有血液学改变的人群)中评价上述因素对MCA血流速率的相关性。从门诊透析中心选26名患慢性肾衰非卧床成年志愿者,男15,女11,平均年龄51±16(19～69)岁。排除急性病和脑血管病。透析前作TCD检查并同时取动脉分支血样作血细胞计数、血液流变学检查和血气分析等,数据经统计学处理。
Transcranial Doppler (TCD) is a noninvasive technique for the determination of cerebral blood flow velocity. Hemodynamic factors, such as vascular diameter, compliance and pressure gradient, are the main determinants of blood flow velocity. Other related factors are age, arterial CO 2 partial pressure, hematocrit (Ht) and fibrinogen content. However, in the past the relative importance of age, oxygen content and hemorheology was not tested. The authors evaluated the association of these factors with MCA blood flow rates in patients with chronic renal failure (those with hematological changes). From outpatient dialysis center selected 26 chronic renal failure ambulatory adult volunteers, male 15, female 11, the average age of 51 ± 16 (19 to 69) years of age. Acute and cerebrovascular diseases are excluded. TCD before dialysis for check and take the blood branching artery branch for blood cell count, hemorheological examination and blood gas analysis, the data were statistically processed.