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目的观察麻杏石甘汤联合阿奇霉素序贯治疗小儿支原体肺炎的临床效果。方法收集2015年12月~2016年12月期间我院收治的230例支原体肺炎住院患儿的临床资料,根据入院顺序随机将230例患儿分为治疗组和对照组,每组各115例,两组均采用予止咳、雾化吸入化痰、辅助吸氧等常规辅助治疗。对照组患儿在辅助治疗基础上加用阿奇霉素静脉滴注,治疗组患儿加用麻杏石甘汤联合阿奇霉素序贯治疗。记录两组患儿退烧时间、咳嗽消失时间、肺部啰音消失时间、住院时间,根据《中医临床病症诊断疗效标准》中的相关规定,评估两组患儿治疗效果,并行统计学对比。结果治疗组患儿退烧时间(6.5±1.5)h、咳嗽消失时间(3.8±1.2)d、肺部啰音消失时间(4.6±2.0)d、住院时间(7.2±1.7)d,均明显优于对照组,差异显著,存在统计学意义(P<0.05)。结论麻杏石甘汤联合阿奇霉素序贯治疗小儿支原体肺炎能够有效改善患儿症状,降低了抗生素用量,提高治疗有效率,值得临床推广应用。
Objective To observe the clinical effect of Maxing Shigan Decoction combined with azithromycin in the sequential treatment of Mycoplasma pneumonia in children. Methods The clinical data of 230 children with mycoplasma pneumonia admitted in our hospital from December 2015 to December 2016 were collected. According to the order of admission, 230 children were randomly divided into treatment group and control group, with 115 cases in each group. Both groups were used to give cough, inhalation phlegm, assisted oxygen and other conventional adjuvant therapy. Control children with adjuvant therapy plus azithromycin on the basis of intravenous infusion, the treatment group with the addition of Maxingshigan soup combined with azithromycin sequential treatment. The two groups of children with fever, cough disappear time, pulmonary rales disappear time, hospital stay, according to the relevant provisions of the “diagnostic criteria for clinical symptoms of Chinese medicine” to assess the therapeutic effect of two groups of children, parallel statistical comparison. Results The treatment time was 6.5 ± 1.5 h, 3.8 ± 1.2 days for cough, 4.6 ± 2.0 days for pulmonary rales and 7.2 ± 1.7 days for hospital stay, respectively The difference between the two groups was significant (P <0.05). Conclusion Maxing Shi Gan Tang combined with azithromycin sequential treatment of children with mycoplasma pneumonia can effectively improve the symptoms of children, reducing the amount of antibiotics and improve the treatment efficiency, it is worth promoting the clinical application.