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采用BaKer酵母对氟代烷基酮,酮酯及乙烯化合物进行不对称还原,制备具有光学活性的单氟或多氟化合物。为手性氟化物的合成开创了一条新的途径。本文主要综述近十年来的研究进展。
The asymmetric reduction of fluoroalkyl ketones, ketoesters and vinyl compounds by BaKer yeast was used to prepare optically active monofluoro or polyfluorinated compounds. For the synthesis of chiral fluoride to create a new way. This article mainly summarizes the research progress in the past ten years.