《中国药典》2000年版二部在复方甘草片的鉴别项下采用薄层色谱法,复方甘草片中含多种生物碱,其中吗啡含量较低,所以提取方法较关键。生物碱在碱性条件下游离而转溶于氯仿中,碱性强弱影响了复方甘草片中吗啡提取程度,并且还要避免用水洗涤时吗啡溶解损失。结果常常是样品斑点不 In the 2000 edition of the Chinese Pharmacopoeia, thin layer chromatography was used under the identification of compound licorice tablets. Compound licorice tablets contained many alkaloids. The content of morphine was low, so the extraction method was more critical. Alkaloids are free under alkaline conditions and are dissolved in chloroform. The strength of the alkaloids affects the degree of morphine extraction in compound licorice tablets, and also avoids loss of morphine lysis when washed with water. The result is often that the sample spots are not