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目的:探讨微创软脑膜下小脑扁桃体下疝切除、枕大池重建术治疗Chiari畸形Ⅰ型(CM-Ⅰ)并脊柱侧凸畸形的临床效果。方法:通过对2015年1月至2017年12月在郑州大学附属郑州中心医院脊髓空洞症专科16例接受微创手术治疗的CM-Ⅰ并脊柱侧凸畸形患者进行回顾性研究,将研究对象分为儿童组(8例)和青少年组(8例),脊柱侧弯测量角Cobb角<35°组(6例)和Cobb角≥35°组(10例)进行比较分析。结果:微创手术治疗后,平均随访2年。在儿童组和青少年组中,微创术后脊柱侧凸改善6例(37.5%),恶化5例(31.3%),无变化5例(31.3%)。其中儿童组有3例(37.5%)需要行脊柱侧凸矫正手术,青少年组有6例(75.0%)需要行脊柱侧凸矫正手术。Cobb角<35°组和Cobb角≥35°组中,术前Cobb角≥35°组的患者(7/10例,70.00%)比Cobb<35°组的患者(2/6例,33.33%)更需要进行脊柱侧凸矫正手术(n P=0.018)。n 结论:CM-Ⅰ并脊柱侧凸患者Cobb角<35°时行微创软脑膜下小脑扁桃体下疝切除、枕大池重建术干预可能能改善或稳定脊柱侧凸。“,”Objective:To explore the clinical effect of minimally invasive subpial resection of the cerebellar tonsillar and the reconstruction of the cisternoma in the treatment of Chiari malformation type Ⅰ (CM-Ⅰ) combined with scoliosis.Methods:A retrospective study was carried out for 16 CM-Ⅰ scoliosis patients who underwent minimally invasive surgery.The subjects were divided into children group (8 cases) and adolescents group (8 cases), with Cobb angle<35° group(6 cases) and Cobb angle≥35° group(10 cases).Results:After minimally invasive surgery, the average follow-up was 2 years.In the children and adolescent groups, 6 cases (37.5%) of scoliosis improved after accepting minimally invasive surgery, 5 cases (31.3%) worsened, and none changed in 5 cases (31.3%). Among them, 3 cases (37.5%) in the children group required scoliosis correction surgery, and 6 cases (75.0%) in the adolescents group needed scoliosis correction surgery.In the Cobb angle<35°group and the Cobb angle≥35°group, patients in the preoperative Cobb angle≥35°group (7/10 cases, 70.00%) required more treatment than those in the Cobb angle<35°group (2/6 cases, 33.33%) scoliosis correction surgery (n P=0.018).n Conclusions:In CM-Ⅰ patients combined with scoliosis, when the Cobb angle is less than 35°, minimally invasive subpial resection of the cerebellar tonsillar and reconstruction of the cisternoma may improve or stabilize the scoliosis.