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目的:观察血必净注射液联合常规疗法治疗五步蛇咬伤患者的临床疗效。方法:将40例患者随机分为对照组和治疗组各20例。对照组给予局部伤口清创、封闭治疗、预防破伤风针注射、抗蛇毒血清及预防性使用抗生素治疗。治疗组在对照组治疗及护理的基础上给予血必净注射液静脉注射治疗。观察2组患者的临床疗效及凝血功能变化。结果:与治疗前比较,2组患者治疗后的凝血功能指标与血小板数量均较治疗前改善(P<0.05)。与对照组治疗后比较,治疗组治疗后各指标情况优于对照组(P<0.05)。临床疗效总有效率治疗组为90.0%,对照组为60.0%,组间比较,差异有显著性意义(P<0.05)。结论:血必净注射液联合常规疗法治疗五步蛇咬伤患者有确切疗效。
Objective: To observe the clinical effect of Xuebijing injection combined with routine therapy in treating patients with five-step snake bite. Methods: 40 patients were randomly divided into control group and treatment group of 20 cases. Control group was given local wound debridement, closed treatment, prevention of tetanus needle injection, anti-snake venom serum and prophylactic antibiotic treatment. Treatment group in the control group on the basis of treatment and care given Xuebijing injection intravenous treatment. The clinical efficacy and coagulation function of two groups were observed. Results: Compared with before treatment, coagulation function index and platelet count of two groups were improved after treatment (P <0.05). Compared with the control group after treatment, the treatment group after treatment indicators better than the control group (P <0.05). The total clinical efficacy of the treatment group was 90.0%, control group was 60.0%, between groups, the difference was significant (P <0.05). Conclusion: Xuebijing injection combined with conventional therapies for the treatment of patients with five-step snake bite have the exact effect.