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目的分析周期性呕吐综合征的临床特点,探讨其病因、诊断及治疗。方法回顾性分析2002年6月至2008年12月诊断的周期性呕吐综合征患儿的临床资料,所有患儿均予赛庚啶、胞二磷胆碱二联治疗,并酌情加用H2-受体拮抗剂及促胃动力药。结果 20例患儿经治疗后全部随访至少1年。3、6个月内均未发现再发,1年内复发4例,第2年起无复发。结论对于反复、突然发作的呕吐患儿经适当的相关检查排除可能的器质性疾病后,应考虑周期性呕吐综合征;对呕吐发作频繁、发作持续时间长的患儿可予赛庚啶、胞二磷胆碱等试验性治疗。
Objective To analyze the clinical features of recurrent vomiting syndrome and to explore the etiology, diagnosis and treatment. Methods The clinical data of children with recurrent vomiting syndrome diagnosed from June 2002 to December 2008 were retrospectively analyzed. All patients were treated with cyproheptadine and citicoline, and H2- Receptor antagonist and gastric motility drug. Results All 20 cases were followed up for at least 1 year after treatment. No recurrence was found in 3 and 6 months, 4 cases relapsed in 1 year and no recurrence in 2 years. Conclusion For recurrent and sudden onset of vomiting in children with appropriate relevant checks to rule out possible organic disease, should consider the periodic vomiting syndrome; frequent vomiting, seizures for a long time in children with cyproheptadine, Citicoline and other experimental treatment.