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从1990 年10 月至1992 年9 月,分别在轮状病毒腹泻的流行季节(每年10 月至次年2 月) 和非流行季节( 每年3月至9 月) 收集广州地区244 例住院新生儿粪便645 份,用核酸电泳(PAGE)技术检测轮状病毒(HRV)RNA。结果显示:新生儿HRV感染很普遍,感染率高达65.16% ,临床表现为轻型腹泻或无症状。流行季节与非流行季节的感染率分别为77.31%和53.63% ,二者感染后发病和无症状的先例亦不相同,流行季节发病率明显高于非流行季节。表明新生儿HRV 感染虽然全年可发生,且存在无症状感染这一特异现象,但与婴幼儿类似,亦有秋冬季流行和发病的趋势。提示新生儿的HRV 传染源主要来自生后环境。在婴幼儿HRV 腹泻的流行季节应重点加强对新生儿的保护。
From October 1990 to September 1992, 244 inpatient newborns in Guangzhou were collected in the epidemic season (from October to February) and non-epidemic season (March to September each year) respectively for rotavirus diarrhea 645 stool samples were tested for rotavirus (HRV) RNA by nucleic acid electrophoresis (PAGE). The results showed that: neonatal HRV infection is common, the infection rate as high as 65.16%, the clinical manifestations of light diarrhea or asymptomatic. The prevalence rates in epidemic season and non-epidemic season were 77.31% and 53.63%, respectively. The incidence and symptom of both cases after infection were also different. The incidence of epidemic season was significantly higher than that of non-epidemic season. Show that neonatal HRV infection may occur throughout the year, and there is a specific phenomenon of asymptomatic infection, but similar with infants and young children, there are autumn and winter epidemics and trends. Tip neonatal source of HRV mainly from postnatal environment. Prevalence of neonatal protection should be emphasized in the infantile season of HRV diarrhea.