论文部分内容阅读
目的:对百令胶囊联合脉血康对早期糖尿病肾病(DN)患者血清胱抑素C(Cys C)的影响进行分析研究。方法:随机抽取2015年1月至2015年10月佛山市高明区人民医院收治的90例早期DN患者纳入研究,根据抽签法分为A组和B组,每组45例,B组予以常规西医治疗,A组予以百令胶囊联合脉血康治疗,检测治疗前后两组患者血清Cys C水平、尿白蛋白排泄率(UAER),血肌酐(Scr),血尿素氮(BUN)并进行对比。结果:治疗前两组患者UAER、Scr、BUN水平均无明显差异,治疗后两组BUN均明显下降,但是组间比较,差异无统计学意义(P>0.05),两组UAER、Scr均明显下降,与治疗前比较差异显著,A组下降幅度大于B组,差异具有统计学意义(P<0.05);治疗前,两组Cys C水平比较,差异无统计学意义(P>0.05),治疗后均明显下降,与治疗前比较差异明显,A组下降幅度大于B组,差异具有统计学意义(P<0.05)。结论:百令胶囊联合脉血康治疗早期DN有助于降低血清Cys C水平,提高临床疗效。
Objective: To study the effect of Bailing capsule combined with pulse Xuekang on serum cystatin C (Cys C) in patients with early diabetic nephropathy (DN). Methods: A total of 90 early DN patients admitted to Gaoming District People’s Hospital of Foshan City from January 2015 to October 2015 were randomly divided into group A and group B, with 45 cases in each group. The patients in group B were treated with routine western medicine The patients in group A were treated with Bailing capsule and pulse Xuekang. The levels of serum Cys C, urinary albumin excretion (UAER), serum creatinine (Scr) and blood urea nitrogen (BUN) were measured before and after treatment. Results: The levels of UAER, Scr and BUN were not significantly different between the two groups before treatment, but the levels of BUN in both groups decreased significantly after treatment, but there was no significant difference between the two groups (P> 0.05) (P <0.05). Before treatment, there was no significant difference in Cys C levels between the two groups (P> 0.05), and the difference was statistically significant After treatment, the difference was significant compared with that before treatment. The decrease in group A was greater than that in group B, the difference was statistically significant (P <0.05). Conclusion: Bailing capsule combined with pulse Xuekang treatment of early DN help to reduce serum Cys C levels and improve clinical efficacy.