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本文旨在研究分析成年人去脂体重(fat free mass,FFM)、脂肪体重(fat mass,FM)和肺通气功能的关系。随机抽取黑龙江省部分地区19~81岁健康成年人群1307人(男性372人,女性935人),测量身高、体重,采用身体成分仪和肺功能仪分别检测FFM、FM和肺通气功能,并采用Pearson相关分析、独立样本t检验和多元逐步回归等统计学方法分析FFM、FM和肺通气功能的关系。结果显示,无论性别,年龄均与脂肪体重指数(FM index,FMI)呈正相关(P<0.001),去脂体重指数(FFM index,FFMI)和用力肺活量(forced vital capacity,FVC)、用力呼气一秒量(forced expiratory volume in one second,FEV1)、最高呼气流量(peak expiratory flow,PEF)、用力呼出25%肺活量时呼气流量(forced expiratory flow at25%of forcedvital capacity,FEF25%)均呈正相关(P<0.01),FMI和FVC、FEV1、FEF75%呈负相关(P<0.05)。男性FMI和最大呼气中段流量(maximal mid-expiratory flow,MMEF)呈负相关(P<0.05)。无论性别,FFMI对于FVC作用大于FMI,而对于FEV1,男性FMI作用大于FFMI,女性则反之。无论性别,FFMI升高,PEF和FEF25%也升高,而FMI对二者无作用。无论性别,FMI升高,FEF75%降低,而FFMI对其无作用。FMI升高,男性MMEF降低,女性无明显改变。本研究结果表明,FFM和FM均是影响肺通气功能的独立因素,反映骨骼肌力的FFM与肺通气功能呈正相关,FM与肺通气功能呈负相关。FFM和FM对肺通气功能作用大小存在差别。
This article aims to study the relationship between adult fat free mass (FFM), fat mass (FM), and pulmonary ventilation. A total of 1,307 healthy adults (372 males and 935 females) aged 19-81 years in some areas of Heilongjiang Province were randomly selected to measure height and weight. FFM, FM and pulmonary ventilation were detected by body composition and pulmonary function tests respectively. Pearson correlation analysis, independent sample t-test and multiple stepwise regression were used to analyze the relationship between FFM, FM and pulmonary function. The results showed that both gender and age were positively correlated with FM index (FMI) (P <0.001), FFM index (FFMI) and forced vital capacity (FVC) Forced expiratory volume at one second (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25% of forcedvital capacity (FEF25%) were positive (P <0.01). There was a negative correlation between FMI and FVC, FEV1 and FEF75% (P <0.05). There was a negative correlation between male FMI and maximal mid-expiratory flow (MMEF) (P <0.05). Regardless of sex, FFMI has a greater effect on FVC than FMI, whereas for FEV1, male FMI has a greater effect than FFMI, whereas women have the opposite. Regardless of sex, FFMI increased, PEF and FEF25% also increased, while FMI had no effect on both. Regardless of sex, FMI increased, FEF75% decreased, while FFMI had no effect on it. FMI increased, male MMEF decreased, no significant change in women. The results of this study show that both FFM and FM are independent factors that affect pulmonary ventilation. FFM that reflects skeletal muscle strength is positively correlated with pulmonary ventilation and FM is negatively correlated with pulmonary ventilation. There is a difference in the effects of FFM and FM on pulmonary ventilation.