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作者对7例急性骨髓硬化症进行研究,并结合文献报导的49例资料作了对比。研究方法:①复查加利福尼亚国家医学癌症中心对骨髓纤维化骨髓活检的切片;②从中挑选符合下述临床和实验特征的病例:a)全血细胞减少,b)很少或无异常的循环红细胞出现,c)骨髓穿刺失败而需活检者,d)脾不大或仅轻度肿大,e)病程快而迅速死亡;③除外已明确为急性骨髓增生症或白血病、再生障碍性贫血等伴骨髓纤维化的病例。经此筛选,所获7例,分析如下。临床表现 7例中6例发病均在50岁以上,女多于男(5∶2)。有发热、疲倦、不适、皮肤易出血等症状。脾轻度肿大仅1例,肝肿大3例。全部均有
The authors studied seven cases of acute myeloid sclerosis and compared them with 49 cases reported in the literature. Research methods: ① review of the National Cancer Center of California bone marrow fibrosis bone marrow biopsy sections; ② selected from the following clinical and experimental characteristics of the cases: a) pancytopenia, b) little or no abnormal circulating red blood cells, c) bone marrow biopsy failed to be biopsy, d) spleen or only mild swelling, e) rapid and rapid course of death; ③ except for acute myeloproliferative disease or acute leukemia, aplastic anemia with bone marrow fibers The case of. After screening, the 7 patients were analyzed as follows. The clinical manifestations of 6 cases in 7 cases were more than 50 years old, more women than men (5: 2). Have fever, tiredness, discomfort, skin bleeding and other symptoms. Spleen mild enlargement in only 1 case, hepatomegaly in 3 cases. All of them