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1955年首次采用~(131)碘-孟加拉红作肝胆闪烁照相。口服胆囊造影(OCG)和静脉胆道造影(IVC)作为诊断胆道疾病的标准方法已有若干年。近来超声图(US)和电子计算机化X线断层扫描术(CAT)也已用于显示胆道。在黄疸病人经皮肝穿刺胆道造影(PTC)和内窥镜逆行胰胆管造影(ERCP)对确定诊断也有一定的价值,但是这些方法都有它的优点和局限性。用~(99m)锝标记亚氨基双醋酸(iminodiacetic acid)的衍化物作胆道闪烁照相重新引起了注意,本报告是根据用~(99m)锝标记的二甲乙酰苯胺亚氨基双醋酸(Dimethylacetanilidoiminodiacetic acid,HIDA)和p-丁基乙酰苯胺亚氨基双醋酸(P-butylacetanili-
In 1955 the first use of ~ (131) iodine - bengal red for hepatobiliary scintigraphy. Oral cholecystography (OCG) and venous cholangiography (IVC) have been the standard methods of diagnosing biliary disease for several years. Recently ultrasonography (US) and computed tomography (CAT) have also been used to visualize the biliary tract. Percutaneous transhepatic cholangiography (PTC) and endoscopic retrograde cholangiopancreatography (ERCP) in patients with jaundice also have some value in the diagnosis, but these methods have their advantages and limitations. This invention is based on the discovery that iminodiacetic acid derivatives derive from bile duct scintigraphy with ~ (99m) technetium. This report is based on the findings that dimethylacetanilidoiminodiacetic acid (dimethylacetanilidoiminodiacetic acid) labeled with ~ (99m) , HIDA) and p-butylacetaniliil-