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目的评估动态对比增强微CT(DCE微CT)在评价乳腺癌小鼠体内对抗血管生成药物治疗反应方面的潜力。方法将20例植入MCF7肿瘤的雌鼠分成对照组和治疗组,对治疗组应用公认有效的抗血管生成药物。所有的雌鼠行DCE微CT检查以做功能参数[相关血流量(rBV)、血管通透性(K)、
Objective To evaluate the potential of dynamic contrast-enhanced micro-CT (DCE micro-CT) in evaluating the response to anti-angiogenic drugs in breast cancer mice. Methods Twenty female rats implanted with MCF7 tumor were divided into control group and treatment group, and the accepted effective antiangiogenic drugs were used in the treatment group. All female rats underwent DCE micro-CT examination to make functional parameters [related blood flow (rBV), vascular permeability (K),