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探讨3种不同的吸痰负压对重型颅脑损伤患者的影响,以寻找重型颅脑损伤患者最佳的吸痰负压。选取某三甲医院的ICU重症颅脑损伤患者46例,当患者出现吸痰指征时,分别以3种不同吸痰负压(-75 mmHg,-150 mmHg,-300 mmHg)对患者行密闭式吸痰,在吸痰前2 min、吸痰后5 min以及吸痰后10 min时记录患者的氧动力学和血流动力学变化,同时记录患者的吸痰时间间隔和效果。吸痰负压为-150 mmHg和-300 mmHg的吸痰效果和吸痰间隔时间要优于-75 mmHg的吸痰负压(p<0.05),且吸痰负压为-150 mmHg时,吸痰的间隔时间最长(78.3±29.8)min;不同吸痰负压组不同时间点的氧分压,二氧化碳分压、收缩压、舒张压和平均动脉压差异有统计学意义(p<0.01),且当吸痰负压是-150 mmHg时、吸痰后5 min和10 min时氧分压相对于吸痰前有明显的改善(p=0.00),当吸痰负压为-300 mmHg时,吸痰后5 min相较于吸痰前收缩压、舒张压和平均动脉压都明显提高,具有统计学意义(p=0.00)。-150 mmHg的吸痰负压是安全和有效的适合重型颅脑损伤患者的吸痰负压。
To investigate the effect of three different suction negative pressure on patients with severe craniocerebral injury in order to find the best suction negative pressure in patients with severe craniocerebral injury. Forty-six patients with ICU severe craniocerebral injury were selected from a top three hospital. When the patient showed indications for suctioning, three different suction negative suction pressures (-75 mmHg, -150 mmHg, -300 mmHg) Suction, 2 min before suction, 5 min after suction and 10 min after suction were recorded in patients with oxygen dynamic and hemodynamic changes, while recording the patient’s suction interval and the effect. Suction sputum negative suction pressure of -150 mmHg and -300 mmHg sputum suction and suction interval should be better than -75 mmHg suction negative pressure (p <0.05), and suction negative pressure -150 mmHg, suction The interval time of sputum was the longest (78.3 ± 29.8) min. There were significant differences in oxygen partial pressure, partial pressure of carbon dioxide, systolic pressure, diastolic pressure and mean arterial pressure at different time points (p <0.01) , And when the suction negative pressure was -150 mmHg, the partial pressure of oxygen was significantly improved compared with that before suction (P = 0.00) at 5 min and 10 min after suctioning, and when suction negative pressure was -300 mmHg , 5 min after sputum aspiration compared with the suction before the systolic blood pressure, diastolic blood pressure and mean arterial pressure were significantly increased, with statistical significance (p = 0.00). Suction negative pressure of -150 mmHg is a safe and effective negative suction for sufferers with severe head injury.