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小檗红碱在黄连等中药材中的自然含量很低,但相关药材中的小檗碱在加热条件下可以转化成小檗红碱而使其含量增加。随着对传统中药材微量成分药理活性和药用安全性的日益关注,小檗红碱在相关中药中的治疗作用及安全性已经引起天然药物学领域专家的重视,本文在参考最新文献的基础上,对小檗红碱的化学合成方法、含量分析方法和药理作用等方面进行综述,拟为相关中药质量研究与药理研究提供参考
Berberine red berberine and other Chinese herbal medicines in the natural content is very low, but the berberine in the relevant herbs in the heating conditions can be converted into berberine and its content increased. With the growing concern about the pharmacological activity and medicinal safety of trace components in traditional Chinese medicinal materials, the therapeutic effect and safety of berberine in relevant Chinese medicines have drawn the attention of experts in the fields of natural pharmacology. Based on the latest literature On the chemical synthesis of berberine, methods of content analysis and pharmacological effects and so on, to be related to the quality of traditional Chinese medicine research and pharmacological research provide a reference