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目的:探讨急性心肌梗死患者早期使用辛伐他汀的疗效,以供临床参考。方法:对我院2010年5月-2011年7月收治的68例急性心肌梗死患者随机分为两组,对照组患者给予常规治疗,实验组患者在对照组患者基础上给予辛伐他汀治疗,比较两组患者心血管事件发生率及血脂情况。结果:实验组心血管事件发生率低于对照组,两组患者比较差异有统计学意义(p<0.05)。实验组血脂指标改善优于对照组,两组患者比较差异有统计学意义(p<0.05)。结论:在急性心肌梗死患者早期治疗中给予辛伐他汀具有较好的疗效,医生要注意观察患者的不良反应,以给予更好的治疗和药物应用。
Objective: To investigate the effect of early use of simvastatin in patients with acute myocardial infarction for clinical reference. Methods: Sixty-eight patients with acute myocardial infarction admitted to our hospital from May 2010 to July 2011 were randomly divided into two groups. Patients in the control group were given routine treatment. Patients in the experimental group were given simvastatin on the basis of the control group, The incidence of cardiovascular events and blood lipids were compared between the two groups. Results: The incidence of cardiovascular events in the experimental group was lower than that in the control group. The difference between the two groups was statistically significant (p <0.05). The improvement of blood lipid in experimental group was better than that in control group, the difference was statistically significant (p <0.05). Conclusions: Simvastatin is effective in the early treatment of patients with acute myocardial infarction. Doctors should pay attention to observe the adverse reactions in patients to give better treatment and drug application.