本文研究了硝酸铈对大白鼠内脏组织、大脑及骨骼肌中一氧化氮、一氧化氮合成酶的影响。结果显示 ,腹腔注射高浓度的稀土后 ,大鼠肝脏、心脏、肾脏、骨骼肌中一氧化氮、一氧化氮合成酶的水平明显增加 ,注射低浓度的稀土后 ,肝脏、肾脏内一氧化氮的量显著增加。提示稀土能够广泛影响机体一氧化氮、一氧化氮合酶的水平 ,一氧化氮有可能参与了稀土的中毒过程。 In this paper, the effects of cerium nitrate on nitric oxide and nitric oxide synthase in visceral tissue, brain and skeletal muscle of rats were studied. The results showed that the levels of nitric oxide and nitric oxide synthase in the liver, heart, kidney and skeletal muscle of rats increased significantly after intraperitoneal injection of high concentration of rare earths. After the injection of low concentration of rare earth, the levels of nitric oxide Significantly increased. Prompted rare earth can widely affect the body’s levels of nitric oxide, nitric oxide synthase, nitric oxide may be involved in the process of rare earth poisoning.