环孢霉素(Cyclosporin,以下简称Cs)是器官移植的新型免疫抑制剂。随着国内应用Cs的日渐增多,其药物相互作用及其毒性应该引起重视。本文根据外文文献对此做一概述。一、Cs与其它药合用: 与强的松龙:Howden等报告Cs合用强的松龙时,可使后者的清除率减少而增强其治疗 Cyclosporin (hereinafter referred to as Cs) is a new immunosuppressive agent for organ transplantation. With the increasing application of Cs in China, its drug interactions and its toxicity should be taken seriously. This article based on foreign literature to make an overview. First, Cs and other drugs combined: and prednisolone: ​​Howden and other reports of Cs combined with prednisolone, can make the latter reduce the clearance rate and enhance their treatment