间质瘤(GIST)是消化道最常见的叶源性肿瘤,长期以来一直被认为是消化道平滑肌肉瘤或神经鞘膜瘤,1983年Ma-zurh和Clark运用电镜和免疫组化重新评估胃间质叶源性肿瘤的组织发生,从而提出GIST的概念,作为这类肿瘤分化方向的临时替代名称。近年来发现该肿瘤存在c-kit基因突变及其蛋 GISTs are the most common type of mesenchymal tumors in the digestive tract and have long been considered as gastrointestinal leiomyosarcoma or schwannoma. In 1983, Ma-Zurh and Clark re-evaluated the gastric compartment with electron microscopy and immunohistochemistry Tissue of the mesenchymal tumor takes place, giving rise to the concept of GIST as a temporary alternative name for the direction of such tumor differentiation. In recent years, the tumor found c-kit gene mutation and its eggs